Clozapine augmentation for treatment-resistant schizoaffective disorder
نویسندگان
چکیده
منابع مشابه
Response after Infection-Associated Rise in Clozapine Levels in Treatment-Resistant Schizoaffective Disorder
The clinical management of patients with treatment-resistant psychotic disorders is still challenging despite years of extensive research. If first-line antipsychotic treatment proves ineffective, clozapine is considered golden standard. Herein, we report on a patient with schizoaffective disorder that initially showed no response to treatment with clozapine and ECT and therefore reached a ther...
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There is considerable evidence that cognitive impairment is a better predictor of work and social function in schizophrenia than are positive and negative symptoms. Atypical antipsychotic drugs have been shown to improve cognitive function in schizophrenia patients, but it is unclear whether this improves patients' ability to gain employment. Data from a prospective longitudinal study was used ...
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OBJECTIVE To evaluate the efficacy and safety of clozapine for treatment-resistant bipolar disorder (TRBD). METHODS A systematic review of randomized controlled studies, open-label prospective studies, and retrospective studies of patients with TRBD was carried out. Interventions included clozapine monotherapy or clozapine combined with other medications. Outcome measures were efficacy and ad...
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Compelling diagnostic definitions and evidence-based treatment recommendations for schizoaffective disorder are lacking, but clinicians can still develop an effective, individualized treatment regimen for patients with this condition. The steps necessary to help patients with schizoaffective disorder reach and maintain remission are to confirm the diagnosis, evaluate the patient's predictors of...
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Substantial changes in cigarette or caffeine consumption may necessitate a dose adjustment of clozapine In 2014, bpacnz published an article on the safer prescribing of clozapine. Since this time, a number of fatalities, along with new research, has reiterated the need for close monitoring of patients treated with this high-risk medicine. Clozapine is often effective for patients with treatment...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2016
ISSN: 1465-1858
DOI: 10.1002/14651858.cd012104